Hyoscyamine 0.125 mg is used to treat many different stomach and intestinal disorders, including peptic ulcer and irritable bowel syndrome. It is also used to control muscle spasms in the bladder, kidneys, or digestive tract, and to reduce stomach acid. Hyoscyamine is sometimes used to reduce tremors and rigid muscles in people with symptoms of Parkinson’s disease. Hyoscyamine is also used as a drying agent to control excessive salivation, runny nose, or excessive sweating. Hyoscyamine may also be used for purposes not listed in this medication guide levsin. hyoscyamine 0.125 mg
Hyoscyamine 0.125 mg is used to provide symptomatic relief of spasms caused by various lower abdominal and bladder disorders including peptic ulcers, irritable bowel syndrome, diverticulitis, pancreatitis, colic, and interstitial cystitis. It has also been used to relieve some heart problems, control some of the symptoms of Parkinson’s disease, as well as for control of abnormal respiratory symptoms and “hyper-mucus secretions” in patients with lung disease. levsin
It is also useful in pain control for neuropathic pain, chronic pain and palliative care – “comfort care” – for those with intractable pain from treatment resistant, untreatable, and incurable diseases. When combined with opioids it increases the level of analgesia (pain relief) obtained. Several mechanisms are thought to contribute to this effect. The closely related drugs atropine and hyoscine and other members of the anticholinergic drug group like cyclobenzaprine, trihexyphenidyl, and orphenadrine are also used for this purpose. When hyoscyamine is used along with opioids or other anti-peristaltic agents, measures to prevent constipation are especially important given the risk of paralytic ileus.
Hyoscyamine 0.125 mg is an antimuscarinic; i.e., an antagonist of muscarinic acetylcholine receptors. It blocks the action of acetylcholine at parasympathetic sites in sweat glands, salivary glands, stomach secretions, heart muscle, sinoatrial node, smooth muscle in the gastrointestinal tract, and the central nervous system. It increases cardiac output and heart rate, lowers blood pressure and dries secretions. It may antagonize serotonin. At comparable doses, hyoscyamine has 98 per cent of the anticholinergic power of atropine. The other major belladonna-derived drug hyoscine (known in the United States as Scopolamine) has 92 per cent of the antimuscarinic potency of atropine
You should not use hyoscyamine if you have urination problems, a stomach or bowel obstruction, severe ulcerative colitis, glaucoma, or myasthenia gravis.
Before taking this medicine
You should not use hyoscyamine if you are allergic to it, or if you have:
a bladder obstruction or other urination problems;
an enlarged prostate;
a stomach or bowel obstruction (including paralytic ileus);levsin
severe ulcerative colitis, or toxic megacolon;
Hyoscyamine is not approved for use by anyone younger than 2 years old.
Tell your doctor if you have ever had:
high blood pressure;
a colostomy or ileostomy;
a thyroid disorder; or
hiatal hernia with GERD (gastroesophageal reflux disease).
It is not known whether this medicine will harm an unborn baby. Tell your doctor if you are pregnant or plan to become pregnant.
It may not be safe to breast-feed while using this medicine. Ask your doctor about any risk.
How should I take hyoscyamine?
Follow all directions on your prescription label and read all medication guides or instruction sheets. Use the medicine exactly as directed.
Always follow directions on the medicine label about giving hyoscyamine to a child.
Swallow an extended-release tablet whole and do not crush, chew, or break it.
Measure liquid medicine carefully. Use the dosing syringe provided, or use a medicine dose-measuring device (not a kitchen spoon).
Remove an orally disintegrating tablet from the package only when you are ready to take the medicine. Place the tablet on your tongue and allow it to dissolve. Swallow several times as the tablet dissolves. You may drink water after the pill has completely dissolved.
Store at room temperature away from moisture and heat.
What happens if I miss a dose?
Take the medicine as soon as you can, but skip the missed dose if it is almost time for your next dose. Do not take two doses at one time.
What happens if I overdose?
Seek emergency medical attention or call the Poison Help line at 1-800-222-1222.
Overdose symptoms may include headache, dizziness, dry mouth, trouble swallowing, nausea, vomiting, blurred vision, hot dry skin, and feeling restless or nervous.
What should I avoid while taking hyoscyamine?
Avoid taking antacids at the same time you take hyoscyamine. Antacids can make it harder for your body to absorb hyoscyamine. If you use an antacid, take it after you have taken hyoscyamine and eaten a meal. levsin
Drinking alcohol with hyoscyamine can cause side effects.
Avoid becoming overheated or dehydrated during exercise and in hot weather. Hyoscyamine can decrease sweating and you may be more prone to heat stroke.
Avoid driving or hazardous activity until you know how this medicine will affect you. Your reactions could be impaired .levsin
Hyoscyamine side effects
Get emergency medical help if you have signs of an allergic reaction: hives; difficult breathing; swelling of your face, lips, tongue, or throat.
Stop using hyoscyamine and call your doctor at once if you have:
anxiety, confusion, hallucinations, unusual thoughts or behavior;
weakness, memory problems;
problems with balance or muscle movement;
pounding heartbeats or fluttering in your chest.
Common side effects may include:
dizziness, drowsiness, feeling weak or tired;
decreased sweating, decreased urination;
dry mouth, decreased sense of taste;
stomach pain, nausea, vomiting, bloating;
sleep problems (insomnia); or
impotence, loss of interest in sex, or trouble having an orgasm.